Inhibin alpha Antikörper (AA 196-366)

Produktnummer ABIN5027320

Der Maus Monoklonal anti-Inhibin alpha Antikörper wird verwendet zum Nachweis von Inhibin alpha in Proben von Human. Er wurde validiert für WB und IHC.

Kurzübersicht für Inhibin alpha Antikörper (AA 196-366) (ABIN5027320)

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Inhibin alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: ABM44F5

Produktdetails anti-Inhibin alpha Antikörper

Bindungsspezifität: AA 196-366

Aufreinigung: Protein G Chromatography

Immunogen: A partial length recombinant Inhibin alpha protein (amino acids 196-366) was used as the immunogen for this antibody.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: WB: 0.5-1, IHC-5-10 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu Inhibin alpha

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Andere Bezeichnung: Inhibin alpha

Hintergrund: Inhibin alpha (INHA) are dimeric glycoproteins that are structurally and functionally related to transforming growth factor-beta and are composed of 1 Alpha-subunit and 1 of 2 beta-subunits (betaA or betaB). Inhibin, first identified as a hormone regulating pituitary FSH secretion, later recognized to act as a tumor suppressor in the gonad and adrenal glands. INHA are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins play important roles in normal gonadal function, including regulation of proliferation, differentiation, and steroidogenesis of Leydig and Sertoli cells via paracrine and autocrine processes.

Molekulargewicht: 35 kDa

Gen-ID: 3623

UniProt: P05111

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion