IDH1 Antikörper (AA 198-414)

Produktnummer ABIN5027284

Der Maus Monoklonal anti-IDH1 Antikörper wird verwendet zum Nachweis von IDH1 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für IDH1 Antikörper (AA 198-414) (ABIN5027284)

Target: IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IDH1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: ABM44B3

Produktdetails anti-IDH1 Antikörper

Bindungsspezifität: AA 198-414

Aufreinigung: Protein G Chromatography

Immunogen: A partial length recombinant IDH1 protein (amino acids 198-414) was used as the immunogen for this antibody

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: IHC: 5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu IDH1

Target: IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))

Andere Bezeichnung: IDH1

Hintergrund: Isocitrate dehydrogenase 1 (IDH1) is a dimeric cytosolic NADP-dependent dehydrogenase that catalyzes decarboxylation of isocitrate into alpha-ketoglutarate. It belongs to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). It serves a significant role in cytoplasmic NADPH production. It is found in the cytoplasm and peroxisomes. IDH1 is of great importance in cell metabolism and energy conversion. Mutations in IDH1 are found in a somatic mosaic fashion in patients with multiple enchondromas.

Gen-ID: 3417

UniProt: O75874

Pathways: Warburg Effekt