RNF31 Antikörper (AA 780-1020)

Produktnummer ABIN5027254

Der Kaninchen Polyklonal Anti-RNF31-Antikörper wurde für WB validiert. Er ist geeignet, RNF31 in Proben von Human zu detektieren.

Kurzübersicht für RNF31 Antikörper (AA 780-1020) (ABIN5027254)

Target: RNF31 (Ring Finger Protein 31 (RNF31))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF31 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RNF31 Antikörper

Bindungsspezifität: AA 780-1020

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant HOIP/RNF31 protein (amino acids 780-1020) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu RNF31

Target: RNF31 (Ring Finger Protein 31 (RNF31))

Andere Bezeichnung: HOIP/RNF31

Hintergrund: RNF31 (ring finger protein 31), also known as HOIP (HOIL-1-interacting protein) is an atypical E3 ubiquitin ligase that belongs to the RBR (RING-between-RING) family of E3 ligases and is the catalytic component of LUBAC (linear ubiquitin chain assembly complex), a multisubunit E3 ligase. Linear ubiquitin chains are assembled by the LUBAC (Linear Ubiquitin Chain Assembly Complex), which plays a critical role in the activation of the NF-kappaB pathway that is involved in various functions, including cell survival and inflammation. RNF31 is essential for the assembly and function of LUBAC and for various processes governing inflammation and immunity in both hematopoietic and nonhematopoietic cells.

Molekulargewicht: 110 Kda

Gen-ID: 55072

UniProt: Q96EP0