RNF31 Antikörper (Middle Region)

Produktnummer ABIN2774753

Zitiert in 8+ Publikationen. Der Kaninchen Polyklonal anti-RNF31 Antikörper (ABIN2774753) detektiert spezifisch RNF31 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Kaninchen, Hund, Meerschweinchen, Pferd und Rind (Kuh).

Kurzübersicht für RNF31 Antikörper (Middle Region) (ABIN2774753)

Target: RNF31 (Ring Finger Protein 31 (RNF31))

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Meerschweinchen, Pferd, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF31 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RNF31 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: RNF31 Antibody - middle region

Sequenz: SLINAHSLDP ATLYEVEELE TATERYLHVR PQPLAGEDPP AYQARLLQKL

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RNF31. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RNF31

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43241-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RNF31 Antikörper (ABIN2774753)

Shibata, Tokunaga, Goto, Komatsu, Gohda, Saeki, Tanaka, Takahashi, Sawasaki, Inoue, Oshiumi, Seya, Nakano, Tanaka, Iwai, Inoue: "HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains." in: PLoS pathogens, Vol. 13, Issue 1, pp. e1006162, (2017) (PubMed).

Lafont, Kantari-Mimoun, Draber, De Miguel, Hartwig, Reichert, Kupka, Shimizu, Taraborrelli, Spit, Sprick, Walczak: "The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death." in: The EMBO journal, Vol. 36, Issue 9, pp. 1147-1166, (2017) (PubMed).

Kupka, De Miguel, Draber, Martino, Surinova, Rittinger, Walczak: "SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes." in: Cell reports, Vol. 16, Issue 9, pp. 2271-80, (2016) (PubMed).

Queisser, Dada, Deiss-Yehiely, Angulo, Zhou, Kouri, Knab, Liu, Stegh, DeCamp, Budinger, Chandel, Ciechanover, Iwai, Sznajder: "HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growth." in: American journal of respiratory and critical care medicine, Vol. 190, Issue 6, pp. 688-98, (2014) (PubMed).

Blackwell, Zhang, Workman, Ting, Iwai, Habelhah: "Two coordinated mechanisms underlie tumor necrosis factor alpha-induced immediate and delayed I?B kinase activation." in: Molecular and cellular biology, Vol. 33, Issue 10, pp. 1901-15, (2013) (PubMed).

Liu, Chen, Cai, Wu, Chen, Wu, Sun, Chen: "MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades." in: eLife, Vol. 2, pp. e00785, (2013) (PubMed).

Smit, Monteferrario, Noordermeer, van Dijk, van der Reijden, Sixma: "The E3 ligase HOIP specifies linear ubiquitin chain assembly through its RING-IBR-RING domain and the unique LDD extension." in: The EMBO journal, Vol. 31, Issue 19, pp. 3833-44, (2012) (PubMed).

Sieber, Lange, Kollmorgen, Erhardt, Quaas, Gontarewicz, Sass, Tiegs, Kreienkamp: "Sharpin contributes to TNF? dependent NF?B activation and anti-apoptotic signalling in hepatocytes." in: PLoS ONE, Vol. 7, Issue 1, pp. e29993, (2012) (PubMed).

Details zu RNF31

Target: RNF31 (Ring Finger Protein 31 (RNF31))

Andere Bezeichnung: RNF31

Hintergrund:

Background Information: PWP2 contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions.

Gene Name: Ring finger protein 31

Alternative Symbols: HOIP, Paul, ZIBRA

Protein Name: E3 ubiquitin-protein ligase RNF31

Molekulargewicht: 120kDa

Gen-ID: 55072

NCBI Accession: NP_060469

UniProt: Q96EP0