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GAPDH Antikörper (AA 120-320)

Dieses Maus Monoklonal-Antikörper erkennt spezifisch GAPDH in WB und IHC. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN5027214

Kurzübersicht für GAPDH Antikörper (AA 120-320) (ABIN5027214)

Target

Alle GAPDH Antikörper anzeigen
GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Reaktivität

  • 240
  • 154
  • 134
  • 64
  • 49
  • 41
  • 28
  • 25
  • 25
  • 19
  • 19
  • 19
  • 15
  • 15
  • 14
  • 13
  • 10
  • 9
  • 8
  • 6
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 179
  • 105
  • 16
  • 9
  • 4
Maus

Klonalität

  • 193
  • 118
Monoklonal

Konjugat

  • 192
  • 31
  • 18
  • 16
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GAPDH Antikörper ist unkonjugiert

Applikation

  • 258
  • 110
  • 98
  • 81
  • 61
  • 56
  • 36
  • 36
  • 16
  • 15
  • 15
  • 15
  • 7
  • 6
  • 5
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)

Klon

ABM22C5
  • Bindungsspezifität

    • 35
    • 22
    • 16
    • 14
    • 12
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 120-320

    Kreuzreaktivität

    Maus

    Aufreinigung

    Protein G Chromatography

    Immunogen

    A partial length recombinant GAPDH protein (amino acids 120-320) was used as the immunogen for this antibody.

    Isotyp

    IgG1 kappa
  • Applikationshinweise

    WB: 0.5-1 μg/mL, IHC: 5 μg/mL

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    0.5 mg/mL

    Buffer

    PBS containing 0.05 % BSA, PH 7.4

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Target

    GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

    Andere Bezeichnung

    GAPDH

    Hintergrund

    GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase) is an enzyme best known for its role in glycolysis. However, extra-glycolytic functions of GAPDH have been described, including regulation of protein expression via RNA binding. GAPDH binds to numerous AREs (adenine-uridine rich elements) from various mRNA 3'-untranslated regions in vitro and in vivo despite its lack of a canonical RNA binding motif. GAPDH specifically catalyzes the simultaneous phosphorylation and oxidation of glyceraldehyde 3-phosphate using NAD+ (Nicotinamide Adenine Dinucleotide) as a cofactor to produce glycerate 1,3-biphosphate and NADH. In addition to its role in energy production, GAPDH has been implicated in many cellular processes including DNA repair tRNA export, membrane fusion and transport, endocytosis and nuclear membrane assembly, and cell death.

    Molekulargewicht

    36 kDa

    Gen-ID

    2597

    UniProt

    P04406
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