Endoglin Antikörper (AA 43-287)

Produktnummer ABIN5027184

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Endoglin in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Endoglin Antikörper (AA 43-287) (ABIN5027184)

Target: Endoglin (ENG)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Endoglin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: ABM46D3

Produktdetails anti-Endoglin Antikörper

Bindungsspezifität: AA 43-287

Aufreinigung: Protein G Chromatography

Immunogen: A partial length recombinant Endoglin protein (amino acids 43-287) was used as the immunogen for this antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu Endoglin

Target: Endoglin (ENG)

Andere Bezeichnung: Endoglin

Hintergrund: ENG (Endoglin) is an integral membrane glycoprotein that serves as a co receptor for members of the transforming growth factor-beta superfamily of proteins. It is a type I membrane glycoprotein expressed as a disulfide-linked homodimer on human vascular endothelial cells and is implicated in a dominant vascular dysplasia known as hereditary hemorrhagic telangiectasia as well as in preeclampsia. Endoglin suppresses human prostate cancer (PCa) cell invasion. It has been identified as a candidate tumor-suppressor gene in esophageal squamous cell carcinoma (ESCC).

Molekulargewicht: 70 kDa

Gen-ID: 2022

UniProt: P17813