CD73 Antikörper (AA 145-346)
Kurzübersicht für CD73 Antikörper (AA 145-346) (ABIN5027098)
Target
Alle CD73 (NT5E) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 145-346
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Aufreinigung
- Protein G Chromatography
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Immunogen
- A partial length recombinant CD73 protein (amino acids 145-346) was used as the immunogen for this antibody.
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Isotyp
- IgG2a kappa
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anti-5'-Nucleotidase, Ecto (CD73) (NT5E) (AA 520-550), (C-Term) antibody
NT5E Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB02846 unconjugated
anti-5'-Nucleotidase, Ecto (CD73) (NT5E) (AA 30-250) antibodyNT5E Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 4G6B10 unconjugated
anti-5'-Nucleotidase, Ecto (CD73) (NT5E) (AA 29-500) antibodyNT5E Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-5'-Nucleotidase, Ecto (CD73) (NT5E) (AA 290-550) antibodyNT5E Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-5'-Nucleotidase, Ecto (CD73) (NT5E) (AA 30-250) antibodyNT5E Reaktivität: Human WB, IHC, FACS, ELISA Wirt: Maus Monoclonal 4G6E3 unconjugated
anti-5'-Nucleotidase, Ecto (CD73) (NT5E) antibodyNT5E Reaktivität: Human WB, IHC, FACS, IF, StM Wirt: Maus Monoclonal NT5E-2503 unconjugated
anti-5'-Nucleotidase, Ecto (CD73) (NT5E) antibodyNT5E Reaktivität: Human WB, IHC, FACS, ELISA, IF, StM, Coat Wirt: Maus Monoclonal NT5E-2545 unconjugated
anti-5'-Nucleotidase, Ecto (CD73) (NT5E) (AA 48-527) antibodyNT5E Reaktivität: Rind (Kuh) WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-5'-Nucleotidase, Ecto (CD73) (NT5E) antibody (PE)NT5E Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal AD2 PE
anti-5'-Nucleotidase, Ecto (CD73) (NT5E) (AA 29-500) antibodyNT5E Reaktivität: Human WB, IHC, ICC, IP Wirt: Maus Monoclonal D1 unconjugated
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Applikationshinweise
- WB: 2-4 μg/mL, IHC: 5 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- PBS containing 0.05 % BSA, PH 7.4
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
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Andere Bezeichnung
- CD73
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Hintergrund
- CD73, also known as ecto-5'-nucleotidase, is a glycosyl-phosphatidylinositol linked plasma membrane glycoprotein that is expressed on multiple cell types and in different tissues. It is a key enzyme in the regulation of purinergic signaling and inflammatory reactions. It hydrolyzes extracellular AMP into adenosine, which dampens immune cell activation, and reduces leukocyte trafficking CD73 potently suppresses antitumor T cell responses through its ability to generate adenosine. It has also emerged as an important regulator of tissue homeostasis and pathophysiologic responses related to immunity, inflammation, pain, ischemia, tissue fibrosis and cancer.
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Molekulargewicht
- 63 kDa
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Gen-ID
- 4907
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UniProt
- P21589
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Pathways
- Synaptic Membrane, Ribonucleoside Biosynthetic Process
Target
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