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CLEC4E Antikörper

CLEC4E Reaktivität: Human WB Wirt: Maus Monoclonal ABM42C6 unconjugated
Produktnummer ABIN5026978
  • Target Alle CLEC4E Antikörper anzeigen
    CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))
    Reaktivität
    • 30
    • 17
    • 2
    Human
    Wirt
    • 24
    • 6
    Maus
    Klonalität
    • 25
    • 5
    Monoklonal
    Konjugat
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CLEC4E Antikörper ist unkonjugiert
    Applikation
    • 25
    • 16
    • 13
    • 13
    • 13
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Aufreinigung
    Protein G Chromatography
    Immunogen
    A full length human CLEC4E protein was used as the immunogen for this antibody.
    Klon
    ABM42C6
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product CLEC4E Primärantikörper
  • Applikationshinweise
    WB: 2-4 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    PBS containing 0.05 % BSA, PH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
  • Target
    CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))
    Andere Bezeichnung
    CLEC4E (CLEC4E Produkte)
    Synonyme
    CLECSF9 antikoerper, MINCLE antikoerper, C86253 antikoerper, Clecsf9 antikoerper, Mincle antikoerper, CLEC4E antikoerper, C-type lectin domain family 4 member E antikoerper, C-type lectin domain family 4, member e antikoerper, C-type lectin domain family 4, member E antikoerper, CLEC4E antikoerper, Clec4e antikoerper, LOC611538 antikoerper
    Hintergrund
    CLEC4E (C-type lectin domain family 4, member E), also called as Mincle, is a type II transmembrane C-type lectin receptor that specifically binds to the cord factor TDM (trehalose-6,6-dimycolate), a unique glycolipid of mycobacterial cell-surface components, and activates immune cells to confer adjuvant activity. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. CLEC4E is mainly expressed in myeloid cells, such as macrophages and neutrophils and possesses a single carbohydrate-recognition domain (CRD) in the extracellular region. It is associated with FcRgamma chain, an immunoreceptor tyrosine-based activation motif (ITAM)-containing adaptor, and acts as an activating receptor that senses damaged cells. CLEC4E is also a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPbeta) and may play a role in inflammation.
    Molekulargewicht
    25 kDa
    Gen-ID
    26253
    UniProt
    Q9ULY5
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