TYK2 Antikörper (pTyr1054, pTyr1055) (AbBy Fluor® 750)

Produktnummer ABIN5012125

Der Kaninchen Polyklonal Anti-TYK2-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, TYK2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für TYK2 Antikörper (pTyr1054, pTyr1055) (AbBy Fluor® 750) (ABIN5012125)

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TYK2 Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-TYK2 Antikörper (AbBy Fluor® 750)

Bindungsspezifität: pTyr1054, pTyr1055

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Tyk2 around the phosphorylation site of Tyr1054/1055

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TYK2

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Andere Bezeichnung: Tyk2 +

Hintergrund:

Synonyms: TYK2Tyr1054/1055, Tyk2phospho Y1054/1055, TYK2 phospho Tyr1054/1055, p-TYK2 Tyr1054/1055, JTK 1, JTK1, TYK 2, Non receptor tyrosine protein kinase 2, Non receptor tyrosine protein kinase TYK2, Protein Tyrosine Kinase 2, Tyrosine kinase 2, TYK2_HUMAN, Non-receptor tyrosine-protein kinase TYK2.

Background: This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq].

Gen-ID: 7297

Pathways: JAK-STAT Signalweg, Hepatitis C