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CRLF2 Antikörper (Center)

Der Kaninchen Polyklonal Anti-CRLF2-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, CRLF2 in Proben von Human zu detektieren.
Produktnummer ABIN501083

Kurzübersicht für CRLF2 Antikörper (Center) (ABIN501083)

Target

Alle CRLF2 Antikörper anzeigen
CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Reaktivität

  • 48
  • 25
  • 19
Human

Wirt

  • 49
  • 21
  • 3
Kaninchen

Klonalität

  • 52
  • 21
Polyklonal

Konjugat

  • 25
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CRLF2 Antikörper ist unkonjugiert

Applikation

  • 39
  • 27
  • 26
  • 17
  • 12
  • 8
  • 7
  • 6
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 15
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    Spezifität

    This antibody detects CRLF2.

    Kreuzreaktivität (Details)

    Species reactivity (tested):Human

    Aufreinigung

    Peptide affinity chromatography

    Immunogen

    TSLP Receptor antibody was raised against a 19 amino acid peptide from near the center of human TSLP receptor.

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS containing 0.02 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target

    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

    Andere Bezeichnung

    CRLF2

    Hintergrund

    Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells, co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal transduction and is inhibited by SOCS-1. Despite its predicted molecular weight, TSLP-R often migrates at a higher molecular weight in SDS-PAGE.Synonyms: Cytokine receptor-like 2, Cytokine receptor-like factor 2, IL-XR, ILXR, TSLPR, Thymic stromal lymphopoietin protein receptor

    Gen-ID

    64109

    UniProt

    Q9HC73
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