TRIM8 Antikörper (AbBy Fluor® 680)

Produktnummer ABIN5009971

Der Kaninchen Polyklonal Anti-TRIM8-Antikörper wurde für WB und IF (p) validiert. Er ist geeignet, TRIM8 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für TRIM8 Antikörper (AbBy Fluor® 680) (ABIN5009971)

Target: TRIM8 (Tripartite Motif Containing 8 (TRIM8))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM8 Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-TRIM8 Antikörper (AbBy Fluor® 680)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TRIM8/RNF27

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TRIM8

Target: TRIM8 (Tripartite Motif Containing 8 (TRIM8))

Andere Bezeichnung: RNF27

Hintergrund:

Synonyms: Lioblastoma expressed ring finger protein, Ring finger protein 27, RNF27, RP11-47A8.4, TRIM8, Tripartite mot containing 8, Tripartite mot protein TRIM8, TRIM8_HUMAN.

Background: The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM8 (tripartite motif containing 8), also known as GERP (glioblastoma-expressed RING finger protein) or RNF27 (RING finger protein 27), is a 551 amino acid protein that is thought to function as an E3 ubiquitin-protein ligase that promotes SOCS-1 proteasomal degradation. As a widely expressed homodimer, TRIM8 localizes to nuclear bodies and contains two B box-type zinc fingers and one RING-type zinc finger. TRIM8 is expressed in lung, heart, brain and skeletal muscle, with low levels detected in intestine, placenta, leukocytes and liver. The gene encoding TRIM8 maps to human chromosome 10q24.32.

Gen-ID: 81603

UniProt: Q9BZR9