TRIM8 Antikörper (N-Term)

Produktnummer ABIN2778368

Der Kaninchen Polyklonal anti-TRIM8 Antikörper wird verwendet zum Nachweis von TRIM8 in Proben von Human, Ratte, Maus, Hund, Rind (Kuh), Kaninchen, Pferd, Schwein und Zebrafisch (Danio rerio). Er wurde validiert für WB und IHC.

Kurzübersicht für TRIM8 Antikörper (N-Term) (ABIN2778368)

Target: TRIM8 (Tripartite Motif Containing 8 (TRIM8))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Kaninchen, Pferd, Schwein, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TRIM8 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: TRIM8 Antibody - N-terminal region

Sequenz: RGCIGEAWAK DSGLVRCPEC NQAYNQKPGL EKNLKLTNIV EKFNALHVEK

Homologie: Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TRIM8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39655-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu TRIM8

Target: TRIM8 (Tripartite Motif Containing 8 (TRIM8))

Andere Bezeichnung: TRIM8

Hintergrund:

Background Information: TRIM8 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.

Gene Name: Tripartite motif containing 8

Alternative Symbols: GERP, RNF27

Protein Name: Probable E3 ubiquitin-protein ligase TRIM8

Molekulargewicht: 61kDa

Gen-ID: 81603

NCBI Accession: NP_112174

UniProt: Q9BZR9