TLR11 Antikörper (C-Term)

Produktnummer ABIN500942

Der Kaninchen Polyklonal Anti-TLR11-Antikörper wurde für WB, IF und EIA validiert. Er ist geeignet, TLR11 in Proben von Maus zu detektieren.

Kurzübersicht für TLR11 Antikörper (C-Term) (ABIN500942)

Target: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-TLR11 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects TLR11 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Mouse

Aufreinigung: Ion exchange chromatography

Immunogen: TLR11 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy-terminus of mouse TLR11.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 0.5 to 1 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu TLR11

Target: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Andere Bezeichnung: TLR11

Hintergrund: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR11 is one of three mouse TLRs that lack a human ortholog (6). It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system (7).Synonyms: Gm287, Toll-like receptor 11

Gen-ID: 239081

NCBI Accession: NP_991388

Pathways: Activation of Innate immune Response