PRKD3 Antikörper (pSer41) (AbBy Fluor® 750)

Produktnummer ABIN5009192

Dieses Anti-PRKD3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PRKD3 in WB, IF (cc) und IF (p). Geeignet für Ratte.

Kurzübersicht für PRKD3 Antikörper (pSer41) (AbBy Fluor® 750) (ABIN5009192)

Target: PRKD3 (Protein Kinase D3 (PRKD3))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKD3 Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PRKD3 Antikörper (AbBy Fluor® 750)

Bindungsspezifität: pSer41

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human PRKD3 around the phosphorylation site of Ser41 [RL(p-S)NG]

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PRKD3

Target: PRKD3 (Protein Kinase D3 (PRKD3))

Andere Bezeichnung: PRKD3

Hintergrund:

Synonyms: PRKD3phospho S41, PKD/PKC_Phospho-Ser41, EPK 2, EPK2, EPK-2, nPKC nu, nPKCnu, nu, PKCnu, PKD 3, PKD3, PRK D3, PRKCN, PRKD 3, PRKD3, Protein kinase C, Protein kinase C nu, Protein kinase C nu type, Protein kinase D3, Protein kinase EPK 2, Protein kinase EPK2, Serine threonine protein kinase, Serine/threonine protein kinase D3.

Background: Protein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.