PVRL4 Antikörper (AbBy Fluor® 680)

Produktnummer ABIN5007376

Der Kaninchen Polyklonal Anti-PVRL4-Antikörper wurde für WB validiert. Er ist geeignet, PVRL4 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PVRL4 Antikörper (AbBy Fluor® 680) (ABIN5007376)

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PVRL4 Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Western Blotting (WB)

Produktdetails anti-PVRL4 Antikörper (AbBy Fluor® 680)

Kreuzreaktivität: Human, Maus

Homologie: Rat,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nectin 4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PVRL4

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Andere Bezeichnung: Nectin 4

Hintergrund:

Synonyms: Ig superfamily receptor LNIR, Nectin 4, poliovirus receptor-related 4, PRR4, poliovirus receptor related 4.

Background: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

Gen-ID: 59341

Pathways: Cell-Cell Junction Organization