CD180 Antikörper (C-Term)

Produktnummer ABIN500626

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD180 in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für CD180 Antikörper (C-Term) (ABIN500626)

Target: CD180 (CD180 Molecule (CD180))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD180 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-CD180 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects CD180 / RP105 at C-term).

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Peptide affinity chromatography

Immunogen: RP105 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human RP105.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu CD180

Target: CD180 (CD180 Molecule (CD180))

Andere Bezeichnung: CD180 / RP105

Hintergrund: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses.. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins. One such protein is RP105, a recently identified homolog to TLR4 that, with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. It has also been suggested that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes. Despite its predicted molecular weight, RP105 often migrates at 95 - 105 kDa.Synonyms: LY64, Lymphocyte antigen 64, Radioprotective 105 kDa protein

Gen-ID: 4064

UniProt: Q99467

Pathways: Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades