MEX3C Antikörper (C-Term)

Produktnummer ABIN500618

Der Kaninchen Polyklonal Anti-MEX3C-Antikörper wurde für WB und EIA validiert. Er ist geeignet, MEX3C in Proben von Human, Maus und Ratte zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für MEX3C Antikörper (C-Term) (ABIN500618)

Target: MEX3C (Mex-3 Homolog C (C. Elegans) (MEX3C))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEX3C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-MEX3C Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects Rkhd2.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: Rkhd2 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human RKHD2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-MEX3C Antikörper (ABIN500618)

Li, Li, Liu, Jin, Lu: "Oocyte-Specific Expression of Mouse MEX3C652AA in the Ovary and Its Potential Role in Regulating Maternal Fos mRNA." in: Biology of reproduction, Vol. 94, Issue 5, pp. 115, (2017) (PubMed).

Details zu MEX3C

Target: MEX3C (Mex-3 Homolog C (C. Elegans) (MEX3C))

Andere Bezeichnung: MEX3C / RKHD2

Hintergrund: Rkhd2, also known as MEX3C is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd2, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. It has been suggested that genetic variations in Rkhd2 may be associated with susceptibility to essential hypertension type 8. Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.Synonyms: RING finger and KH domain-containing protein 2, RING finger protein 194, RNA-binding protein MEX3C, RNF194

Gen-ID: 51320

NCBI Accession: NP_057710

UniProt: Q5U5Q3