JunD Antikörper (AA 245-347) (AbBy Fluor® 680)

Produktnummer ABIN5005685

Dieses Anti-JunD-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von JunD in WB, IF (p) und IF (cc). Geeignet für Ratte.

Kurzübersicht für JunD Antikörper (AA 245-347) (AbBy Fluor® 680) (ABIN5005685)

Target: JunD (JUND) (Jun D Proto-Oncogene (JUND))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JunD Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-JunD Antikörper (AbBy Fluor® 680)

Bindungsspezifität: AA 245-347

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Jun D

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu JunD

Target: JunD (JUND) (Jun D Proto-Oncogene (JUND))

Andere Bezeichnung: Jun D

Hintergrund:

Synonyms: jun D proto-oncogene, JUND1, AP-1, JUND, JUND1, MGC6245, MGC72300.

Background: The cJun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus vjun oncogene. JunB and JunD have been shown to be almost identical to cJun in their C terminal regions, which are involved in dimerization and DNA binding, whereas their N terminal domains, which are involved in transcriptional activation, diverge. JunB is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage, including non-AUG codons, results in the production of different isoforms.

Gen-ID: 3727