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PIGY Antikörper (C-Term)

PIGY Reaktivität: Human, Maus WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500497
  • Target Alle PIGY Antikörper anzeigen
    PIGY (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Y (PIGY))
    Bindungsspezifität
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    Human, Maus
    Wirt
    • 5
    Kaninchen
    Klonalität
    • 5
    Polyklonal
    Konjugat
    • 5
    Dieser PIGY Antikörper ist unkonjugiert
    Applikation
    • 5
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects PIG-Y at C-term. It only detects isoform 1 of PIG-Y.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    PIG-Y antibody was raised against a 16 amino acid peptide near the carboxy terminus of human PIG-Y.
    Isotyp
    IgG
  • Applikationshinweise
    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    PIGY (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Y (PIGY))
    Andere Bezeichnung
    PIGY (PIGY Produkte)
    Synonyme
    PIG-Y antikoerper, pig-y antikoerper, Prey antikoerper, Pyurf antikoerper, prey antikoerper, 1810008A14Rik antikoerper, Pigy antikoerper, phosphatidylinositol glycan anchor biosynthesis class Y antikoerper, phosphatidylinositol glycan anchor biosynthesis, class Y antikoerper, Pigy upstream reading frame S homeolog antikoerper, phosphatidylinositol glycan anchor biosynthesis, class Y-like antikoerper, PIGY antikoerper, pigy antikoerper, Pigy antikoerper, pyurf.S antikoerper, Pigyl antikoerper
    Hintergrund
    Glycosylphosphatidylinositol (GPI) lipid anchoring is an important post-translational modification of proteins that takes place in the endoplasmic reticulum. The synthesis of GPI is initiated by GPI-N-acetylglucosaminyltransferase (GPI-GnT), a complex of proteins including PIG-A, PIG-H, PIG-C, GPI1, and DPM2. PIG-Y, the mammalian homolog to yeast Eri1p, is also thought to be involved in the biosynthesis of GPI. The PIG-Y gene encodes two proteins, one of which arises from leaky scanning of the mRNA. Despite its predicted molecular weight, PIG-Y often migrates at 28-30 kDa in SDS-PAGE.Synonyms: PIG-Y, Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y, Phosphatidylinositol-glycan biosynthesis class Y protein
    Gen-ID
    84992
    NCBI Accession
    NP_001036081
    UniProt
    Q3MUY2
    Pathways
    Inositol Metabolic Process
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