CBX3 Antikörper (pSer93) (AbBy Fluor® 750)

Produktnummer ABIN5004831

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CBX3 in IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CBX3 Antikörper (pSer93) (AbBy Fluor® 750) (ABIN5004831)

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBX3 Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CBX3 Antikörper (AbBy Fluor® 750)

Bindungsspezifität: pSer93

Homologie: Human,Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human HP1 gamma around the phosphorylation site of Ser83

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CBX3

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Andere Bezeichnung: HP1 gamma

Hintergrund:

Synonyms: HP1 gamma phospho S93, HP1 gamma phospho Ser93, p-HP1 gamma Ser93, CBX 3, CBX3, Chromobox homolog 3, Chromobox protein homolog 3, HECH, Heterochromatin like protein 1, Heterochromatin protein 1 homolog gamma, Heterochromatin protein HP1 gamma, HP1 gamma homolog, HP1Hs gamma , Modier 2, protein HP1-GAMMA, HP1g, M32, HP1 gamma, MGC118084, CBX3_HUMAN, Modier 2 protein.

Background: HP1 gamma appears to be involved in transcriptional silencing in heterochromatin-like complexes. It recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. HP1 gamma may contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR) and involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Gen-ID: 11335