PCDH12 Antikörper (N-Term)

Produktnummer ABIN500453

Der Kaninchen Polyklonal Anti-PCDH12-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, PCDH12 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für PCDH12 Antikörper (N-Term) (ABIN500453)

Target: PCDH12 (Protocadherin 12 (PCDH12))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDH12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-PCDH12 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects PCDH12. It is predicted to not cross-react with PCDH18.

Aufreinigung: Peptide affinity chromatography

Immunogen: PCDH12 antibody was raised against a 17 amino acid peptide near the amino terminus of human PCDH12.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PCDH12

Target: PCDH12 (Protocadherin 12 (PCDH12))

Andere Bezeichnung: Protocadherin-12 / PCDH12

Hintergrund: Protocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA, further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2,289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling.Synonyms: VE-cad-2, VE-cadherin-2, Vascular cadherin-2, Vascular endothelial cadherin-2

Gen-ID: 51294

NCBI Accession: NP_057664

UniProt: Q9NPG4

Pathways: Cellular Glucan Metabolic Process