ORAI2 Antikörper (C-Term)

Produktnummer ABIN500423

Der Kaninchen Polyklonal anti-ORAI2 Antikörper wird verwendet zum Nachweis von ORAI2 in Proben von Human und Maus. Er wurde validiert für WB, IF und EIA.

Kurzübersicht für ORAI2 Antikörper (C-Term) (ABIN500423)

Target: ORAI2 (ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORAI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-ORAI2 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects ORAI2 at C-term. It is predicted to have no cross-reactivity to ORAI1 or ORAI3.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Peptide affinity chromatography

Immunogen: ORAI2 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human ORAI2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu ORAI2

Target: ORAI2 (ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2))

Andere Bezeichnung: ORAI2

Hintergrund: Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.Synonyms: C7orf19, CAP-binding protein complex-interacting protein 2, CBCIP2, Protein orai-2, TMEM142B, Transmembrane protein 142B

Gen-ID: 80228

UniProt: Q96SN7