ORAI2 Antikörper (C-Term)

Produktnummer ABIN500423

Produktdetails anti-ORAI2 Antikörper

Target: ORAI2 (ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORAI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects ORAI2 at C-term. It is predicted to have no cross-reactivity to ORAI1 or ORAI3.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Peptide affinity chromatography

Immunogen: ORAI2 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human ORAI2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu ORAI2

Target: ORAI2 (ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2))

Andere Bezeichnung: ORAI2 (ORAI2 Produkte)

Synonyme: C7orf19 antikoerper, CBCIP2 antikoerper, MEM142B antikoerper, TMEM142B antikoerper, A730041O15Rik antikoerper, Tmem142b antikoerper, RGD1310213 antikoerper, ORAI2 antikoerper, orai-1 antikoerper, orai1 antikoerper, tmem142a antikoerper, tmem142b antikoerper, LOC100230993 antikoerper, ORAI calcium release-activated calcium modulator 2 antikoerper, ORAI calcium release-activated calcium modulator 2 S homeolog antikoerper, ORAI2 antikoerper, Orai2 antikoerper, orai2.S antikoerper, orai2 antikoerper

Hintergrund: Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.Synonyms: C7orf19, CAP-binding protein complex-interacting protein 2, CBCIP2, Protein orai-2, TMEM142B, Transmembrane protein 142B

Gen-ID: 80228

UniProt: Q96SN7