ORAI2 Antikörper (C-Term)

Produktnummer ABIN6990742

Produktdetails anti-ORAI2 Antikörper

Target: ORAI2 (ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORAI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Spezifität: At least two isoforms of ORAI2 are known to exist, this antibody will detect both isoforms. ORAI antibody is predicted not to cross-react with ORAI1 or ORAI3.

Aufreinigung: ORAI2 Antibody is affinity chromatography purified via peptide column.

Immunogen: ORAI2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human ORAI2. The immunogen is located within the last 50 amino acids of ORAI2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ORAI2 antibody can be used for detection of ORAI2 by Western blot at 1 - 4 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ORAI2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ORAI2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ORAI2

Target: ORAI2 (ORAI Calcium Release-Activated Calcium Modulator 2 (ORAI2))

Andere Bezeichnung: ORAI2 (ORAI2 Produkte)

Synonyme: C7orf19 antikoerper, CBCIP2 antikoerper, MEM142B antikoerper, TMEM142B antikoerper, A730041O15Rik antikoerper, Tmem142b antikoerper, RGD1310213 antikoerper, ORAI2 antikoerper, orai-1 antikoerper, orai1 antikoerper, tmem142a antikoerper, tmem142b antikoerper, LOC100230993 antikoerper, ORAI calcium release-activated calcium modulator 2 antikoerper, ORAI calcium release-activated calcium modulator 2 S homeolog antikoerper, ORAI2 antikoerper, Orai2 antikoerper, orai2.S antikoerper, orai2 antikoerper

Hintergrund: ORAI2 Antibody: Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.

Molekulargewicht: Predicted: 19, 28 kDa

Observed: 29 kDa

Gen-ID: 80228

UniProt: Q96SN7