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LY86 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-LY86-Antikörper wurde für WB, IHC (p) und EIA validiert. Er ist geeignet, LY86 in Proben von Human zu detektieren.
Produktnummer ABIN500258

Kurzübersicht für LY86 Antikörper (C-Term) (ABIN500258)

Target

Alle LY86 Antikörper anzeigen
LY86 (Lymphocyte Antigen 86 (LY86))

Reaktivität

  • 27
  • 19
  • 17
Human

Wirt

  • 38
  • 7
  • 4
Kaninchen

Klonalität

  • 40
  • 9
Polyklonal

Konjugat

  • 22
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser LY86 Antikörper ist unkonjugiert

Applikation

  • 36
  • 14
  • 13
  • 13
  • 10
  • 9
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 15
    • 9
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    This antibody detects MD-1 at C-term.

    Kreuzreaktivität (Details)

    Species reactivity (tested):Human

    Aufreinigung

    Peptide affinity chromatography

    Immunogen

    MD-1 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human MD-1.

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS containing 0.02 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target

    LY86 (Lymphocyte Antigen 86 (LY86))

    Andere Bezeichnung

    LY86 / MD-1

    Hintergrund

    Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway.. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.Synonyms: Lymphocyte antigen 86, MD1

    Gen-ID

    9450

    NCBI Accession

    NP_004262

    UniProt

    O95711

    Pathways

    Toll-Like Receptors Cascades
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