SEC16B Antikörper (C-Term)

Produktnummer ABIN500212

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SEC16B in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für SEC16B Antikörper (C-Term) (ABIN500212)

Target: SEC16B (SEC16 Homolog B (SEC16B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SEC16B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-SEC16B Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität (Details): Species reactivity (tested):Humna, Mouse, Rat

Aufreinigung: Peptide affinity chromatography

Immunogen: LZTR2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human LZTR2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu SEC16B

Target: SEC16B (SEC16 Homolog B (SEC16B))

Andere Bezeichnung: SEC16B

Hintergrund: LZTR2, also known as RGPR-p117, is a member of the BTB-kelch superfamily and was initially described as a nuclear factor I (NFI) binding protein and transcriptional regulator of the regucalcin gene. LZTR2 is cytoplasmically localized but is thought to translocate to the nucleus, a process mediated by protein kinase C signaling following hormonal stimulation. Recent evidence has suggested that there is a strong correlation of single nucleotide polymorphisms of LZTR2 with obesity in the Japanese population similar to that seen with the TMEM18 gene and the GNPDA2, BDNF, FAIM2, and MC4R genes with obesity in Caucasian populations, suggesting LZTR2 may play a role in metabolism and obesity risk.Synonyms: KIAA1928, LZTR2, Leucine zipper transcription regulator 2, Protein SEC16 homolog B, Protein transport protein Sec16B, RGPR, RGPR-p117, Regucalcin gene promoter region-related protein p117, SEC16B, SEC16S

Gen-ID: 89866

NCBI Accession: NP_149118

UniProt: Q96JE7