ERAS Antikörper (AA 20-120) (AbBy Fluor® 750)

Produktnummer ABIN5002079

Dieses Anti-ERAS-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ERAS in IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für ERAS Antikörper (AA 20-120) (AbBy Fluor® 750) (ABIN5002079)

Target: ERAS (ES cell expressed Ras (ERAS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERAS Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ERAS Antikörper (AbBy Fluor® 750)

Bindungsspezifität: AA 20-120

Homologie: Human,Mouse,Rat,Dog,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ERAS/HRAS2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ERAS

Target: ERAS (ES cell expressed Ras (ERAS))

Andere Bezeichnung: ERAS/HRAS2

Hintergrund:

Synonyms: E ras, E-Ras, ecat5, Embryonic stem cell expressed Ras, Embryonic stem cell-expressed Ras, Eras, ES cell expressed Ras, GTPase ERas, Ha-Ras2, HRAS2, HRASP, MGC126691, MGC126693, OTTHUMP00000065857, RASE_HUMAN, Small GTPase protein E Ras, v Ha ras Harvey rat sarcoma viral oncogene homolog pseudogene, v Ha ras Harvey rat sarcoma viral oncogene homolog 2.

Background: ERAS belongs to the small GTPase superfamily. Ras family. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. The ERas gene is expressed in embryonic stem (ES) cells and promotes their in vitro proliferation and tumorigenicity. ERas-null ES cells maintain pluripotency but show significantly reduced growth and tumorigenicity, which are rescued by expression of ERas complementary DNA or by activated phosphatidylinositol-3-OH kinase.

Gen-ID: 3266