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ENPP1 Antikörper (AA 41-140) (AbBy Fluor® 750)

This anti-ENPP1 antibody (ABIN5001963) is a Rabbit Polyclonal antibody detecting ENPP1 in WB, IF (cc), IF (p). Suitable for Mouse.
Produktnummer ABIN5001963

Kurzübersicht für ENPP1 Antikörper (AA 41-140) (AbBy Fluor® 750) (ABIN5001963)

Target

Alle ENPP1 Antikörper anzeigen
ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))

Reaktivität

  • 45
  • 34
  • 15
  • 7
  • 4
Maus

Wirt

  • 79
  • 5
  • 2
  • 1
Kaninchen

Klonalität

  • 82
  • 5
Polyklonal

Konjugat

  • 33
  • 13
  • 11
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ENPP1 Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation

  • 70
  • 25
  • 25
  • 17
  • 13
  • 13
  • 11
  • 7
  • 5
  • 4
  • 4
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 10
    • 9
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 41-140

    Kreuzreaktivität

    Maus

    Homologie

    Human,Rat,Dog,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human ENPP1

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))

    Andere Bezeichnung

    ENPP1

    Hintergrund

    Synonyms: M6S1, NPP1, NPPS, PC-1, PCA1, ARHR2, COLED, PDNP1, Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, E-NPP 1, Membrane component chromosome 6 surface marker 1, Phosphodiesterase I/nucleotide pyrophosphatase 1, Plasma-cell membrane glycoprotein PC-1, ENPP1, PC1

    Background: By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity and function.

    Gen-ID

    5167

    UniProt

    P22413

    Pathways

    Regulation of Carbohydrate Metabolic Process
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