POLK Antikörper (AA 1-100) (AbBy Fluor® 680)

Produktnummer ABIN5001359

This anti-POLK antibody (ABIN5001359) is a Rabbit Polyclonal antibody detecting POLK in FACS. Suitable for Human.

Kurzübersicht für POLK Antikörper (AA 1-100) (AbBy Fluor® 680) (ABIN5001359)

Target: POLK (Polymerase (DNA Directed) kappa (POLK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLK Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Flow Cytometry (FACS)

Produktdetails anti-POLK Antikörper (AbBy Fluor® 680)

Bindungsspezifität: AA 1-100

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNA Polymerase Kappa/POLK

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu POLK

Target: POLK (Polymerase (DNA Directed) kappa (POLK))

Andere Bezeichnung: DNA Polymerase Kappa/POLK

Hintergrund:

Synonyms: DNA polymerase kappa, DINB protein, Short=DINP, POLK_HUMAN.

Background: DNA polymerase lambda (pol Kappa), also designated DNA polymerase Kappa or Pol Beta2, is a low-fidelity polymerase which plays a role in both spontaneous and DNA damage-induced mutagenesis. Encoded by the POLL gene, pol Kappa is a member of the DNA polymerase type-X family. Pol Kappa extends primer-terminal mispairs opposite nondamaged DNA templates, suggesting that it may assist in extending mismatched base pairs during normal DNA replication. In addition, pol Kappa may play a role in the mutagenic bypass of T-T dimers. Proliferating cell nuclear antigen (PCNA), a protein essential to DNA replication, interacts with pol Kappa and thus influences the ability of pol Kappa to synthesize DNA.

Gen-ID: 51426

Pathways: DNA Reparatur