IL-34 Antikörper (N-Term)

Produktnummer ABIN500016

Dieses Anti-IL-34-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IL-34 in WB und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für IL-34 Antikörper (N-Term) (ABIN500016)

Target: IL-34 (IL34) (Interleukin 34 (IL34))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-34 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-IL-34 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to IL-34.

Kreuzreaktivität (Details): Species reactivity (tested):Human brain tissue.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: IL-34 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-34.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 0.25 - 0.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu IL-34

Target: IL-34 (IL34) (Interleukin 34 (IL34))

Andere Bezeichnung: Interleukin-34 / IL34

Hintergrund: Interleukin-34 (IL-34) was identified through a functional screening of a library of secreted proteins after transfection of an embryonic kidney cell line with recombinant cDNAs. Flow cytometry and monocyte viability assays demonstrated increased survival and/or proliferation of monocytes induced by IL-34 and specific binding of IL-34 to CD14+ monocytes. IL-34 is a second ligand to the colony stimulating factor (CSF)-1 receptor in addition to CSF1. Like CSF1, IL-34 stimulates phosphorylation of ERK1 and ERK2 in human monocytes and induces differentiation of bone marrow cells into macrophages. Despite its predicted molecular weight, IL-34 will often run at higher molecular weight in SDS-PAGE.Synonyms: C16orf77, IL-34

Gen-ID: 146433

UniProt: Q6ZMJ4

Pathways: RTK Signalweg