IL23A Antikörper (N-Term)

Produktnummer ABIN499998

Dieses Anti-IL23A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IL23A in WB, IHC (p) und EIA. Geeignet für Human und Maus.

Kurzübersicht für IL23A Antikörper (N-Term) (ABIN499998)

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL23A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-IL23A Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to Il-23.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: IL-23 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-23.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu IL23A

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Andere Bezeichnung: Interleukin-23 alpha / IL23A

Hintergrund: Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes (3,4). Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF

Gen-ID: 51561

UniProt: Q9NPF7

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation