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CEP57 Antikörper (AA 51-150) (AbBy Fluor® 750)

This anti-CEP57 antibody (ABIN4999922) is a Rabbit Polyclonal antibody detecting CEP57 in IF (cc), IF (p). Suitable for Human.
Produktnummer ABIN4999922

Kurzübersicht für CEP57 Antikörper (AA 51-150) (AbBy Fluor® 750) (ABIN4999922)

Target

Alle CEP57 Antikörper anzeigen
CEP57 (Centrosomal Protein 57kDa (CEP57))

Reaktivität

  • 45
  • 3
  • 2
  • 1
Human

Wirt

  • 41
  • 4
Kaninchen

Klonalität

  • 44
  • 1
Polyklonal

Konjugat

  • 21
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CEP57 Antikörper ist konjugiert mit AbBy Fluor® 750

Applikation

  • 24
  • 20
  • 12
  • 12
  • 6
  • 5
  • 5
  • 3
  • 3
  • 2
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 51-150

    Homologie

    Human,Mouse,Rat,Dog,Horse

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human CEP57

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    CEP57 (Centrosomal Protein 57kDa (CEP57))

    Andere Bezeichnung

    CEP57

    Hintergrund

    Synonyms: Centrosomal protein 57 kDa, Centrosomal protein of 57 kDa, Cep57, Cep57 protein, CEP57_HUMAN, FGF2 interacting protein, FGF2-interacting protein, KIAA0092, MVA2, PIG8, proliferation inducing protein 8, Testis specic protein 57, Testis-specic protein 57, Translokin, TSP57.

    Background: CEP57 (centrosomal protein 57 kDa), also known as PIG8, TSP57 or Translokin, is a 500 amino acid protein that localizes to both the nucleus and the cytoplasm, specifically associating with microtubules at the centrosome. Expressed ubiquitously, CEP57 exists as a homodimer that functions to mediate the mitogenic activity and nuclear translocation of FGF-2, an internalized growth factor, thereby regulating FGF-2 signaling pathways. Additionally, CEP57 is thought to play a role in spermatogenesis, possibly via the indirect regulation of gene expression. Human CEP57 shares 88 % sequence identity with its mouse and bovine orthologs, suggesting a highly conserved role between species. Multiple isoforms of CEP57 exist due to alternative splicing events.

    Pathways

    M Phase, Maintenance of Protein Location, Protein targeting to Nucleus, Growth Factor Binding
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