HINT1 Antikörper (Center)

Produktnummer ABIN499948

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HINT1 in WB, IF und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für HINT1 Antikörper (Center) (ABIN499948)

Target: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HINT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-HINT1 Antikörper

Bindungsspezifität: Center

Spezifität: This antibody reacts to HINT1.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: HINT1 antibody was raised against a 17 amino acid peptide near the center of the human HINT1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu HINT1

Target: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Andere Bezeichnung: HINT1

Hintergrund: Histidine triad nucleotide-binding protein 1 (HINT1) is a member of the histidine triad (HIT) protein family, a group of small nucleotide-binding and -hydrolyzing proteins. HINT1 interacts with several diverse proteins and has been suggested to have tumor suppressive activities. HINT1 catalyzes the hydrolysis of adenosine 5'-monophoramidate substrates such as AMP-morpholidate, but its enzymatic function does not appear to play a role in its tumor suppression. Recent experiments demonstrate that HINT1 forms a complex with POSH and JNK in vivo, inhibiting AP-1 activity and the phosphorylation of c-Jun, and this action could contribute to the tumor suppressor activity of HINT1. Other studies raise the possibility of HINT1 as a candidate gene for schizophrenia.Synonyms: Adenosine 5'-monophosphoramidase, HINT, HINT1, Histidine triad nucleotide-binding protein 1, PKCI-1, PKCI1, PRKCNH1, Protein kinase C inhibitor 1, Protein kinase C-interacting protein 1

Gen-ID: 3094

NCBI Accession: NP_005331

UniProt: P49773