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HAX1 Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-HAX1-Antikörper wurde für WB und EIA validiert. Er ist geeignet, HAX1 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN499946

Kurzübersicht für HAX1 Antikörper (N-Term) (ABIN499946)

Target

Alle HAX1 Antikörper anzeigen
HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reaktivität

  • 62
  • 21
  • 18
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 52
  • 9
  • 1
Kaninchen

Klonalität

  • 54
  • 8
Polyklonal

Konjugat

  • 33
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HAX1 Antikörper ist unkonjugiert

Applikation

  • 52
  • 29
  • 16
  • 13
  • 13
  • 7
  • 7
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 15
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Spezifität

    This antibody reacts to HAX1B.

    Aufreinigung

    Affinity chromatography purified via peptide column

    Immunogen

    Hax1b antibody was raised against a 10 amino acid peptide near the amino terminus of human Hax1b.

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western Blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C.
  • Target

    HAX1 (HCLS1 Associated Protein X-1 (HAX1))

    Andere Bezeichnung

    HAX1

    Hintergrund

    The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting. At least four isoforms of Hax1 are known to exist. This antibody is predicted to recognize Hax1b.Synonyms: HAX-1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1, HS1BP1

    Gen-ID

    10456

    NCBI Accession

    NP_001018238

    UniProt

    O00165

    Pathways

    Regulation of Actin Filament Polymerization
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