Calcineurin B Antikörper (pTyr106) (AbBy Fluor® 680)

Produktnummer ABIN4998919

Der Kaninchen Polyklonal Anti-Calcineurin B-Antikörper wurde für IF (cc) und IF (p) validiert. Er ist geeignet, Calcineurin B in Proben von Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für Calcineurin B Antikörper (pTyr106) (AbBy Fluor® 680) (ABIN4998919)

Target: Calcineurin B (CAN)

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calcineurin B Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Calcineurin B Antikörper (AbBy Fluor® 680)

Bindungsspezifität: pTyr106

Kreuzreaktivität: Zebrafisch (Danio rerio)

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig,Drosophila

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated syntheticphosphopeptide derived from human Calcineurin B around the phosphorylation site of Tyr106

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Calcineurin B

Target: Calcineurin B (CAN)

Andere Bezeichnung: Calcineurin B

Hintergrund:

Synonyms: Calcineurin B phospho Y106, Calcineurin B phospho Tyr106, p-Calcineurin B Tyr106, Calcineurin subunit B type 1, CALNB1, CANB1_HUMAN, Cna2, CNB, CNB1, OTTHUMP00000201960, OTTHUMP00000201961, Ppp3r1, PPP3R1 protein phosphatase 3 formerly 2B, regulatory subunit B, alpha isoform, alpha isoform calcineurin B, type I, calcineurin B, type I 19 kDa, protein phosphatase3 formerly2B, regulatory subunit B, alpha isoform antibody Protein phosphatase 2B regulatory subunit 1, Protein phosphatase 2B regulatory subunit B alpha, protein phosphatase 3 formerly 2B, regulatory subunit B, 19 kDa, alpha isoform calcineurin B, type I, Protein phosphatase 3 regulatory subunit B alpha, Protein phosphatase 3 regulatory subunit B alpha isoform 1.

Background: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2B family comprises subfamily members PP2B-A alpha, PP2B-A Beta and PP2B-A Gamma. Two additional regulatory subunits been identified, designated PP2B-B1 and PP2B-B2.

Gen-ID: 5534

Pathways: Cellular Glucan Metabolic Process, VEGF Signaling