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FGF4 Antikörper (C-Term)

Dieses Anti-FGF4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FGF4 in WB, EIA und IF. Geeignet für Human und Maus.
Produktnummer ABIN499836

Kurzübersicht für FGF4 Antikörper (C-Term) (ABIN499836)

Target

Alle FGF4 Antikörper anzeigen
FGF4 (Fibroblast Growth Factor 4 (FGF4))

Reaktivität

  • 69
  • 25
  • 15
  • 5
  • 2
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 70
  • 10
  • 1
  • 1
Kaninchen

Klonalität

  • 71
  • 11
Polyklonal

Konjugat

  • 44
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FGF4 Antikörper ist unkonjugiert

Applikation

  • 43
  • 34
  • 28
  • 20
  • 14
  • 13
  • 13
  • 8
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA), Immunofluorescence (IF)
  • Bindungsspezifität

    • 15
    • 11
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    This antibody reacts to FGF4.

    Aufreinigung

    Affinity chromatography purified via peptide column

    Immunogen

    FGF4 antibody was raised against a 18 amino acid peptide near the carboxy terminus of the human FGF4.

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western Blot: 0.5 - 1 μg/mLImmunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C.
  • Target

    FGF4 (Fibroblast Growth Factor 4 (FGF4))

    Andere Bezeichnung

    FGF4

    Hintergrund

    Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development.Synonyms: Fibroblast growth factor 4, HST, HST-1, HSTF1, Heparin secretory-transforming protein, Heparin-binding growth factor 4, KS3, Transforming protein KS3

    Gen-ID

    2249

    UniProt

    P08620

    Pathways

    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance
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