FEZ1 Antikörper (C-Term)

Produktnummer ABIN499830

Der Kaninchen Polyklonal anti-FEZ1 Antikörper (ABIN499830) detektiert spezifisch FEZ1 in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für FEZ1 Antikörper (C-Term) (ABIN499830)

Target: FEZ1 (Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FEZ1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-FEZ1 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to FEZ1.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: FEZ1 antibody was raised against a 19 amino acid peptide from near the carboxy terminus of human FEZ1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu FEZ1

Target: FEZ1 (Fasciculation and Elongation Protein zeta 1 (Zygin I) (FEZ1))

Andere Bezeichnung: Zygin-1

Hintergrund: Similar to its C. elegans homolog UNC-76, mammalian FEZ1, an abundant membrane protein and protein kinase C (PKC)-Z substrate, is involved in axonal guidance. Following phosphorylation by PKC-Z, FEZ1 translocates from the plasma membrane to the cytoplasm. FEZ1 is then able to interact with a number of proteins involved in axonal outgrowth and cellular transport such as DISC1, a candidate gene for schizophrenia, as well as kinesin-1, a microtubule-based motor protein. FEZ1 also interacts with proteins involved in transcriptional regulation and chromatin remodeling, suggesting that FEZ1 may have nuclear regulatory functions in addition to those for neuronal development. At least two distinct isoforms of FEZ1 are known to exist. Despite its predicted molecular weight, FEZ1 will often run at higher molecular weight in SDS-PAGE.Synonyms: FEZ1, Fasciculation and elongation protein zeta-1, Zygin I

Gen-ID: 9638

UniProt: Q99689