EPH Receptor A10 Antikörper (N-Term)

Produktnummer ABIN499800

Dieses Anti-EPH Receptor A10-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von EPH Receptor A10 in WB und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für EPH Receptor A10 Antikörper (N-Term) (ABIN499800)

Target: EPH Receptor A10 (EPHA10)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor A10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-EPH Receptor A10 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody reacts to EphA10.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: EphA10 antibody was raised against a 14 amino acid peptide of near the amino terminus of human EphA10.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu EPH Receptor A10

Target: EPH Receptor A10 (EPHA10)

Andere Bezeichnung: EphA10

Hintergrund: Eph receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility of neuronal and endothelial cells in central nervous system function and in development. Eph receptors can be divided into two subgroups: EphA and EphB. In mammals, the EphA class consists of eight members (EphA 1-7 and 10) that in general bind to ephrin-A members linked to the cell membrane through a glycosylphosphatidylinositol linkage. The EphB class consists of six members (EphB 1-6) that in general bind ephrin-B members that transverse the cell membrane. The Ephrin / EPH signaling pathway networks with the WNT signaling pathway during embryogenesis, tissue regeneration, and carcinogenesis. Recent studies show that Eph/EFN might be relevant in normal B-cell biology and could represent new potential prognostic markers and therapeutic targets for CLL.Synonyms: EPH receptor A10, Ephrin type-A receptor 10, FLJ16103

Gen-ID: 284656

NCBI Accession: NP_001092909

UniProt: Q4G0R4

Pathways: RTK Signalweg