C1QTNF2 Antikörper

Produktnummer ABIN499665

Dieses Anti-C1QTNF2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von C1QTNF2 in WB, IF und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für C1QTNF2 Antikörper (ABIN499665)

Target: C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C1QTNF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-C1QTNF2 Antikörper

Spezifität: CTRP2 antibody was raised against recombinant human CTRP2.

Aufreinigung: Affinity Purified

Immunogen: Recombinant mouse CTRP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: CTRP2 antibody can be used for the detection of CTRP2 at 1 μg/mL. Caco-2cell lysate can be used as positive control. These proteins are often highly modifiedpost-translationally and migrate in SDS-PAGE at positions other than their predicted size. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu C1QTNF2

Target: C1QTNF2 (C1q and Tumor Necrosis Factor Related Protein 2 (C1QTNF2))

Andere Bezeichnung: C1QTNF2

Hintergrund: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation (3).Synonyms: CTRP2, Complement C1q tumor necrosis factor-related protein 2

Gen-ID: 114898

NCBI Accession: NP_114114

UniProt: Q9BXJ5