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Adrenomedullin Antikörper (AA 1-100) (AbBy Fluor® 680)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Adrenomedullin in IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Ratte.
Produktnummer ABIN4996167

Kurzübersicht für Adrenomedullin Antikörper (AA 1-100) (AbBy Fluor® 680) (ABIN4996167)

Target

Alle Adrenomedullin (ADM) Antikörper anzeigen
Adrenomedullin (ADM)

Reaktivität

  • 72
  • 53
  • 18
  • 11
  • 11
  • 2
  • 2
  • 1
  • 1
  • 1
Ratte

Wirt

  • 125
  • 22
  • 2
  • 1
Kaninchen

Klonalität

  • 128
  • 22
Polyklonal

Konjugat

  • 77
  • 25
  • 15
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Adrenomedullin Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation

  • 87
  • 65
  • 40
  • 38
  • 31
  • 25
  • 25
  • 12
  • 9
  • 7
  • 6
  • 6
  • 4
  • 4
  • 3
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 15
    • 14
    • 14
    • 8
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100

    Kreuzreaktivität

    Ratte

    Homologie

    Human,Mouse,Dog,Cow,Pig

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human ADM

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    Adrenomedullin (ADM)

    Andere Bezeichnung

    Adrenomedullin

    Substanzklasse

    Hormone

    Hintergrund

    Synonyms: Adrenomedullin, ADM, AM, Contains, RecName, Proadrenomedullin N-20 terminal peptide, ProAM N-terminal 20 peptide, ProAM-N20, PAMP, ProAM-N20, ADML_HUMAN.

    Background: Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintenance of cardiovascular functioning. In hypertensive patients, the level of ADM in plasma is up-regulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions. ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion.

    Gen-ID

    133

    Pathways

    Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
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