14-3-3 zeta Antikörper (pSer58) (AbBy Fluor® 680)

Produktnummer ABIN4995748

Der Kaninchen Polyklonal Anti-14-3-3 zeta-Antikörper wurde für WB und FACS validiert. Er ist geeignet, 14-3-3 zeta in Proben von Human zu detektieren.

Kurzübersicht für 14-3-3 zeta Antikörper (pSer58) (AbBy Fluor® 680) (ABIN4995748)

Target: 14-3-3 zeta (YWHAZ)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser 14-3-3 zeta Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-14-3-3 zeta Antikörper (AbBy Fluor® 680)

Bindungsspezifität: pSer58

Spezifität: This antibody will react with all 14-3-3 proteins containing the conserved motif RS(S-p)WR.

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human 14-3-3 protein zeta/delta around the phosphorylation site of Ser58 [RS(p-S)WR]

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu 14-3-3 zeta

Target: 14-3-3 zeta (YWHAZ)

Andere Bezeichnung: 14-3-3 protein zeta/ delta

Hintergrund:

Synonyms: YWHAEphospho S58, YWHAZphospho S58, 14 3 3, 14 3 3 protein beta, 14 3 3 protein beta/alpha, 14 3 3 protein zeta, 14-3-3 protein beta/alpha, KCIP 1, Protein 1054, Protein kinase C inhibitor protein 1, YWHAB, YWHAZ, GW128, HS1, KCIP-1, YWHAE, YWHAA, 1433Z_HUMAN, Full=14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1.

Background: Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation amoung many other functions.

Gen-ID: 7534, 7529, 10971

Pathways: Apoptose, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location