CASP14 Antikörper (C-Term)

Produktnummer ABIN499557

Dieses Anti-CASP14-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CASP14 in WB, IHC (p) und EIA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für CASP14 Antikörper (C-Term) (ABIN499557)

Target: CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CASP14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-CASP14 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody reacts to Caspase-14.

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Caspase-14 antibody was raised against a 16 amino acid peptide from near the carboxy- terminus of human caspase-14.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: Caspase-14 antibody can be used for the detection of caspase-14 at 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu CASP14

Target: CASP14 (Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))

Andere Bezeichnung: Caspase-14

Hintergrund: Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Caspase-14 is highly expressed in embryonic but not adult tissues. It is processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in the keratinocyte terminal differentiation, which is important for the formation of the skin barrier.Synonyms: CASP-14, CASP14

Gen-ID: 12365

NCBI Accession: NP_033939

UniProt: O89094