Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CARD10 Antikörper

Dieses Anti-CARD10-Antikörper ist ein Rabbit Polyclonal-Antikörper zur Detektion von CARD10 in WB, IF, EIA. Geeignet für Human, Mouse.
Produktnummer ABIN499533

Kurzübersicht für CARD10 Antikörper (ABIN499533)

Target

Alle CARD10 Antikörper anzeigen
CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Reaktivität

  • 29
  • 6
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 29
  • 1
Kaninchen

Klonalität

  • 29
  • 1
Polyklonal

Konjugat

  • 18
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CARD10 Antikörper ist unkonjugiert

Applikation

  • 18
  • 15
  • 6
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • Spezifität

    CARD10 antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human CARD10.

    Aufreinigung

    Immunoaffinity

    Immunogen

    Murine CARD10 / Caspase recuitment domain family 10 / CARMA3 / Bimp1 Peptide

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western BLot: CARD10 antibody can be used for detection of CARD10 at 5 - 10 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C.
  • Target

    CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

    Andere Bezeichnung

    CARD10 / CARMA3

    Hintergrund

    Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, Bcl-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD10 (1). This protein belongs to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules (2). CARD 10 interacts with Bcl-10, a Bcl protein that promotes apoptosis, caspase-9 maturation and activation of NF-kappaB (1,3). CARD 10 and the related protein CARMA1 also associate with NEMO, the regulatory subunit of the IkappaK complex (4), demonstrating its importance in the regulation of NF-kappaB transcription factor activation.Synonyms: CARD-containing MAGUK protein 3, Caspase recruitment domain-containing protein 10

    Gen-ID

    29775

    UniProt

    F1BA47

    Pathways

    S100 Proteine
Sie sind hier:
Chat with us!