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beta Actin Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch beta Actin in WB, IF und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte und wurde in 1 Publikation erwähnt.
Produktnummer ABIN499441

Kurzübersicht für beta Actin Antikörper (C-Term) (ABIN499441)

Target

Alle beta Actin (ACTB) Antikörper anzeigen
beta Actin (ACTB) (Actin, beta (ACTB))

Reaktivität

  • 197
  • 138
  • 116
  • 55
  • 45
  • 43
  • 40
  • 27
  • 27
  • 25
  • 17
  • 15
  • 11
  • 10
  • 7
  • 7
  • 6
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 116
  • 103
  • 5
  • 1
  • 1
Kaninchen

Klonalität

  • 113
  • 111
Polyklonal

Konjugat

  • 160
  • 11
  • 11
  • 9
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser beta Actin Antikörper ist unkonjugiert

Applikation

  • 191
  • 79
  • 77
  • 47
  • 46
  • 44
  • 32
  • 27
  • 13
  • 13
  • 7
  • 6
  • 6
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 41
    • 17
    • 16
    • 14
    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Spezifität

    Beta-actin antibody was raised against a 16 amino acid peptide from near the carboxy-terminus of human beta-actin.

    Aufreinigung

    Affinity chromatography purified via peptide column

    Immunogen

    Human b-actin / Beta actin (C-Terminus) Peptide

    Isotyp

    IgG
  • Applikationshinweise

    ELISA. Western Blot: beta-actin antibody can be used for the detection of beta-actin at 1 - 2 μg/mL. Immnocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C.
  • Ghate, Hazra, Sarkar, Mandal: "Heartwood extract of Acacia catechu induces apoptosis in human breast carcinoma by altering bax/bcl-2 ratio." in: Pharmacognosy magazine, Vol. 10, Issue 37, pp. 27-33, (2014) (PubMed).

  • Target

    beta Actin (ACTB) (Actin, beta (ACTB))

    Andere Bezeichnung

    Actin beta / ACTB

    Hintergrund

    Actins are highly conserved proteins that are involved in cell motility, structure and integrity, processes that are crucial for tissue development and the development of organism (reviewed in 1). The actin cytoskeleton is one of the principal drivers of cell motility and is capable of responding to complex signaling cascades. Recent evidence suggests that it may play key roles in regulating apoptosis and aging (2). beta actin is one of six different actin isoforms which have been identified. Like GAPDH, Β-actin is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.Synonyms: Actin cytoplasmic 1, Beta-Actin

    Gen-ID

    60

    UniProt

    P60709

    Pathways

    Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction
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