ARHGAP18 Antikörper (C-Term)

Produktnummer ABIN499333

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ARHGAP18 in WB, IF und EIA. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für ARHGAP18 Antikörper (C-Term) (ABIN499333)

Target: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGAP18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Produktdetails anti-ARHGAP18 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: ARHGAP18 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human ARHGAP18.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: ARHGAP18 antibody can be used for detection of ARHGAP18 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu ARHGAP18

Target: ARHGAP18 (rho GTPase Activating Protein 18 (ARHGAP18))

Andere Bezeichnung: ARHGAP18

Hintergrund: ARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins known to be encoded in the human genome. Rho proteins belong to the Ras superfamily that is composed of over 50 members divided into six families, including Ras, Sar, Rho, Ran, Rab and Arf. Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. ARHGAP18 is linked to Ras, and thus, to EGFR-mediated proliferation, migration and differentiation. ARHGAP18 is precisely contained within chromosome 6q22-24, which has been shown to be linked to schizophrenia, suggesting that ARHGEP18 may play a role in this condition.Synonyms: MacGAP, Rho GTPase-activating protein 18, Rho-type GTPase-activating protein 18

Gen-ID: 93663

NCBI Accession: NP_277050

UniProt: Q8N392