ANAPC7 Antikörper (C-Term)

Produktnummer ABIN499303

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ANAPC7 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für ANAPC7 Antikörper (C-Term) (ABIN499303)

Target: ANAPC7 (Anaphase Promoting Complex Subunit 7 (ANAPC7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANAPC7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-ANAPC7 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: APC7 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human APC7.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: APC7 antibody can be used for detection of APC7 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu ANAPC7

Target: ANAPC7 (Anaphase Promoting Complex Subunit 7 (ANAPC7))

Andere Bezeichnung: APC7 / ANAPC7

Hintergrund: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC7 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC7 is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with various transcription coactivators.Synonyms: Anaphase-promoting complex subunit 7, Cyclosome subunit 7

Gen-ID: 51434

NCBI Accession: NP_057322

UniProt: Q4KMX6