Serotonin Receptor 3B Antikörper (Internal Region)

Produktnummer ABIN499176

Produktdetails anti-Serotonin Receptor 3B Antikörper

Target: Serotonin Receptor 3B (HTR3B)

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: C-SNYLQTQDQT DQQE

Spezifität: This antibody detects Serotonin receptor 3B (Internal).

Kreuzreaktivität (Details): Species reactivity (tested):Human

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the internal region (near C-terminus) of the protein sequence according to NP_006019.1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1: 16000 (limit dilution). Western blot: 1-3 μg/mL. Approx 51 kDa band observed in Human Brain (Cerebral Cortex,Hippocampus and Amygdala) lysates (calculated MW of 50.1 kDa according toNP_006019.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C up to one week or (in aliquots) at -20 °C for longer.

Details zu Serotonin Receptor 3B

Target: Serotonin Receptor 3B (HTR3B)

Abstract: HTR3B Produkte

Synonyme: HTR3B antikoerper, 5-HT3B antikoerper, 5-hydroxytryptamine receptor 3B antikoerper, 5-hydroxytryptamine (serotonin) receptor 3B antikoerper, HTR3B antikoerper, Htr3b antikoerper

Hintergrund: There are 4 main groups of receptors which bind the neurotransmitter serotonin: 5HT1, 5HT2 5HT3 and 5HT4. 5HT3B receptor is subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin). This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Through interactions with these receptors, serotonin is able to exert a wide variety of physiological functions. 5HT3 receptors are cation-selective transmitter-gated ion channels. 5HT3B receptor mutations have been implicated in depression.Synonyms: 5-HT3-B, 5-HT3B, 5-hydroxytryptamine receptor 3B

Gen-ID: 9177

NCBI Accession: NP_006019

UniProt: O95264

Pathways: Synaptic Membrane