Decorin Antikörper (Internal Region)

Produktnummer ABIN499170

Der Ziege Polyklonal anti-Decorin Antikörper (ABIN499170) detektiert spezifisch Decorin in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Rind (Kuh), Schwein und Meerschweinchen.

Kurzübersicht für Decorin Antikörper (Internal Region) (ABIN499170)

Target: Decorin (DCN)

Reaktivität: Human, Rind (Kuh), Schwein, Meerschweinchen

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Decorin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Decorin Antikörper

Bindungsspezifität: Internal Region

Sequenz: C-KISRVDAASL KGLNN

Spezifität: This antibody detects Decorin (Internal). It is expected to recognize the three reported isoforms a, b and c (NP_001911.1, NP_598011.1, NP_598012.1 resp.). Reported variants NP_598010.1 and NP_001911.1 represent identical protein.

Kreuzreaktivität (Details): Species reactivity (expected):Cow, pig, caviaSpecies reactivity (tested):Human

Aufreinigung: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the internal region of the protein sequence according to NP_001911.1, NP_598011.1, NP_598012.1

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: limit dilution 1: 8000. Western blot: 0.5-2 μg/mL. Approx 38 kDa band observed in Human Kidney lysates(calculated MW of 39.8 kDa according to NP_001911.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C up to one week or (in aliquots) at -20 °C for longer.

Details zu Decorin

Target: Decorin (DCN)

Andere Bezeichnung: Decorin

Hintergrund: Decorin is a member of the small, leucine rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF beta. It is believed that decorin also plays a role in the cell cycle of chondrocytes.Synonyms: Bone proteoglycan II, DCN, PG-S2, PG40, SLRR1B

Gen-ID: 1634

NCBI Accession: NP_001911

UniProt: P07585

Pathways: Glycosaminoglycan Metabolic Process