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EIF4E Antikörper (pSer209)

EIF4E Reaktivität: Human, Ratte, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN498734
  • Target Alle EIF4E Antikörper anzeigen
    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
    Bindungsspezifität
    • 38
    • 15
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer209
    Reaktivität
    • 124
    • 63
    • 51
    • 19
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Ratte, Maus
    Wirt
    • 106
    • 17
    • 2
    Kaninchen
    Klonalität
    • 99
    • 26
    Polyklonal
    Konjugat
    • 58
    • 9
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser EIF4E Antikörper ist unkonjugiert
    Applikation
    • 97
    • 51
    • 41
    • 27
    • 27
    • 26
    • 16
    • 15
    • 14
    • 13
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody detects endogenous levels of eIF4E protein only when phosphorylated at Ser209.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography
    Reinheit
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product EIF4E Primärantikörper
  • Applikationshinweise
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
    Andere Bezeichnung
    EIF4E (EIF4E Produkte)
    Hintergrund
    The initiation of protein synthesis in eukaryotic cells is regulated by interactions between protein initiation factors and RNA molecules. The eukaryotic initiation complex eIF4F exists in vitro as a trimeric complex of eIF4G, eIF4E, and eIF4A. Together, the complex allows ribosome binding to mRNA by inducing the unwinding of mRNA secondary structures. eIF4E is a 25 kDa protein that binds to the mRNA Synonyms: EIF-4E, EIF4EL1, EIF4F, Eukaryotic translation initiation factor 4E, eIF-4F 25 kDa subunit, mRNA cap-binding protein
    Molekulargewicht
    approx. 25 kDa
    Gen-ID
    1977
    NCBI Accession
    NP_001959
    UniProt
    P06730
    Pathways
    BCR Signaling
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