Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1.0 mg/mL
Buffer
PBS pH ~7.2, 0.05 % Sodium Azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
BMP-3A antikoerper, PBMP3 antikoerper, 9130206H07 antikoerper, 9530029I04Rik antikoerper, BMP3 antikoerper, BMP-3 antikoerper, wu:fk96e01 antikoerper, zgc:153939 antikoerper, xBMP-3 antikoerper, bone morphogenetic protein 3 antikoerper, bone morphogenetic protein 3 L homeolog antikoerper, BMP3 antikoerper, Bmp3 antikoerper, bmp3 antikoerper, bmp3.L antikoerper
Hintergrund
Bone morphogenic proteins (BMPs) are members of the TGFbeta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFbeta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.Synonyms: BMP-3A, BMP3A, Bone morphogenetic protein 3, Osteogenin