Cathepsin D Antikörper
Kurzübersicht für Cathepsin D Antikörper (ABIN498665)
Target
Alle Cathepsin D (CTSD) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Spezifität
- This antibody detects endogenous levels of Cathepsin D protein. (region surrounding Lys345)
-
Aufreinigung
- Affinity chromatography
-
Reinheit
- > 95 % by SDS-PAGE
-
-
-
-
Applikationshinweise
-
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1,0 mg/mL
-
Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freezing and thawing.
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- Cathepsin D (CTSD)
-
Andere Bezeichnung
- Cathepsin D
-
Hintergrund
- The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsins may also cleave some protein precursors, thereby releasing regulatory peptides. The promoter region of the cathepsin D gene contains five Sp1 binding sites and four AP-2 binding sites.Synonyms: CPSD, CTSD
-
Molekulargewicht
- approx. 45 kDa
-
Gen-ID
- 1509
-
NCBI Accession
- NP_001900
-
UniProt
- P07339
-
Pathways
- Peptide Hormone Metabolism
Target
-